Kai He Selected Research

coptisine

9/2017	The protective effect of coptisine on experimental atherosclerosis ApoE-/- mice is mediated by MAPK/NF-κB-dependent pathway.
1/2017	Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
4/2016	Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters.
9/2015	Coptisine attenuates obesity-related inflammation through LPS/TLR-4-mediated signaling pathway in Syrian golden hamsters.
2/2015	The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.

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Kai He Research Topics

Disease

29	Neoplasms (Cancer) 05/2022 - 10/2008
9	Neoplasm Metastasis (Metastasis) 05/2022 - 10/2008
8	Body Weight (Weight, Body) 01/2021 - 10/2011
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2018
6	Inflammation (Inflammations) 06/2022 - 09/2015
5	Breast Neoplasms (Breast Cancer) 01/2022 - 10/2008
5	Lung Neoplasms (Lung Cancer) 01/2021 - 05/2016
4	Cholangiocarcinoma 01/2022 - 02/2003
3	Weight Loss (Weight Reduction) 05/2022 - 01/2017
3	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 06/2015
3	Adenocarcinoma of Lung 01/2022 - 08/2013
3	Insulin Resistance 04/2019 - 09/2015
3	Hyperlipidemias (Hyperlipidemia) 05/2016 - 05/2015
3	Fibrosarcoma 06/2006 - 12/2004
2	Hemorrhage 06/2022 - 01/2021
2	Infections 06/2022 - 07/2007
2	Hypertension (High Blood Pressure) 01/2022 - 01/2016
2	Klatskin Tumor 01/2022 - 01/2021
2	Chronic Obstructive Pulmonary Disease (COPD) 10/2021 - 01/2021
2	Hypoxia (Hypoxemia) 05/2021 - 01/2013
2	Pneumonia (Pneumonitis) 11/2020 - 11/2018
2	Fibrosis (Cirrhosis) 01/2020 - 02/2003
2	Hyperglycemia 01/2020 - 04/2019
2	Pain (Aches) 11/2019 - 10/2010
2	Obesity 09/2017 - 09/2015
2	Hernia (Hernias) 02/2017 - 08/2011
2	Hypercholesterolemia 04/2016 - 02/2015
1	Postoperative Hemorrhage 06/2022
1	Choledocholithiasis 06/2022
1	Sepsis (Septicemia) 06/2022
1	Castleman Disease (Castleman's Disease) 05/2022
1	Hypochromic Anemia (Chlorosis) 04/2022
1	Coma (Comas) 01/2022
1	Hypokinesia (Bradykinesia) 01/2022
1	Lymphoma (Lymphomas) 01/2022
1	Anaphylaxis (Anaphylactic Shock) 01/2022

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2013
8	AlkaloidsIBA 01/2020 - 01/2013
7	Messenger RNA (mRNA)IBA 01/2022 - 05/2015
7	Immune Checkpoint InhibitorsIBA 01/2022 - 12/2017
7	Biomarkers (Surrogate Marker)IBA 08/2021 - 02/2003
6	CholesterolIBA 01/2021 - 02/2015
5	CytokinesIBA 01/2022 - 09/2015
5	Pharmaceutical PreparationsIBA 01/2020 - 01/2013
5	coptisineIBA 09/2017 - 02/2015
4	salicylhydroxamic acid (SHAM)IBA 01/2022 - 01/2017
3	LipopolysaccharidesIBA 06/2022 - 09/2015
3	Long Noncoding RNAIBA 01/2022 - 05/2015
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2017
3	Cadherins (E-Cadherin)IBA 01/2020 - 05/2016
3	Glucose (Dextrose)FDA LinkGeneric 04/2019 - 10/2011
2	Peptides (Polypeptides)IBA 01/2022 - 01/2022
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2019
2	SuspensionsIBA 01/2022 - 01/2021
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2022 - 01/2020
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2013
2	Untranslated RNA (Noncoding RNA)IBA 01/2021 - 05/2015
2	MicroRNAs (MicroRNA)IBA 01/2021 - 09/2020
2	CateninsIBA 01/2020 - 05/2016
2	SaponinsIBA 01/2020 - 05/2012
2	Biological ProductsIBA 01/2020 - 10/2008
2	LigandsIBA 01/2019 - 11/2018
2	LipidsIBA 09/2017 - 09/2015
2	Oxidants (Oxidizing Agents)IBA 09/2017 - 08/2014
2	jatrorrhizineIBA 04/2016 - 09/2014
2	palmatineIBA 04/2016 - 05/2015
2	Hypoglycemic Agents (Hypoglycemics)IBA 02/2016 - 10/2011
2	Blood Glucose (Blood Sugar)IBA 02/2016 - 05/2012
2	LDL CholesterolIBA 01/2016 - 09/2015
2	Triglycerides (Triacylglycerol)IBA 01/2016 - 09/2015
2	oxidized low density lipoproteinIBA 01/2016 - 09/2015
2	Bile Acids and Salts (Bile Acids)IBA 01/2016 - 09/2015
2	EnzymesIBA 06/2015 - 01/2014
2	Janus Kinase 2IBA 11/2005 - 12/2004
1	GABA-A Receptors (GABA(A) Receptor)IBA 06/2022
1	Midazolam (Versed)FDA LinkGeneric 06/2022
1	Neuroprotective AgentsIBA 06/2022
1	Hypnotics and Sedatives (Sedatives)IBA 06/2022
1	gallium Ga 68 dotatateIBA 05/2022
1	Somatostatin Receptors (Somatostatin Receptor)IBA 05/2022
1	methylxanthineIBA 05/2022
1	Ammonium CompoundsIBA 04/2022
1	VenomsIBA 01/2022
1	Factor XIIa (Coagulation Factor XIIa)IBA 01/2022
1	Fibrinolysin FDA Link 01/2022
1	Thrombin FDA Link 01/2022
1	AntigensIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Epinephrine (Adrenaline)FDA LinkGeneric 01/2022

Therapy/Procedure

12	Therapeutics 01/2022 - 05/2012
6	Radiotherapy 01/2022 - 12/2017
5	Drug Therapy (Chemotherapy) 01/2022 - 02/2003
4	Immunotherapy 01/2022 - 12/2017
2	Analgesia 01/2022 - 10/2010
2	Anesthesia 01/2022 - 10/2010
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2020 - 10/2011
2	Oral Administration 02/2016 - 01/2013
1	Length of Stay 06/2022
1	Sutures (Suture) 06/2022
1	Radiofrequency Ablation 03/2022